Yeah i have 5 clients running right now, two gpu's in the same machine and what i shut down is both cores on my 295. The other client running is just an smp client.
I could add another two gpu and smp clients, but its too much.
And i dont really wanna run it on my laptop, if i were to run anything on here it would be just the smp (not gonna stress the 260m that hard since its not user replaceable).