well it depends on how you are with your case. The last LAN party I went to this friend of mine had 3 computers there 2 of which had water cooling inside. It's never recommended to be bumping the case violently lol air or water, but I'm just saying with water cooling, depending on your setup, being a less rough with it as possible is the best option.
It's still a CPU block which weighs considerably less than all current top air solutions....those would sooner fall off than anything.