I installed Windows 10 in a VM, and I haven't had any problems running it virtualized vs on "real" hardware. My first takeaway is that it is a lot more like windows 7, which seems to be the consensus here. I'd be curious to see how it works on a Windows tablet, like the Surface Pro; but as I unfortunately don't have one, I'll ha to be satisfied with running it in a VM.
Microsoft also just released a huge update for the technical preview, that I haven't had a chance to install yet.
I'll have to install the update this weekend and see what all is fixed.