Everyone choosing number 1 is crazy. You can argue that a new computer will get outdated in a few years. But since money is no object, I'm going to pay evga lots of money to make a 16 socket motherboard with like 32 pci-e slots, 512 ddr3 memory slots and at least 96 6gb/s sata ports.
Then I will have Nvidia create 32 super SLI compatible gpus. These gpus can be put in video cards with something like 192GB of GDDR5 ram and have a clock speed of 38GHz.
Each of the ddr3 slots can be loaded with a
32GB ram module. With all 512 slots occupied, my system would have a total of 16384TB of ram.
For the 16 processors, I would have Intel make some kind of uber expensive, 32 core, 64 HT Xeon cpu, buy 16 of them and overclock them to like 15GHz. To cool these cpus, I would buy a lot of phase change cooling systems and have like 12 working in series for each processor.
For my storage, I would raid 95 1TB SSDs together. My hard drive transfer speed would be something like 45GB/second. The 96th sata port would be for a disc drive.
This setup would require somewhere around 22KW to power. So I would need
more than 15 of theseconnected in parallel.