So far I'm seeing lag in accessing menus for Corel Draw and PhotoPaint, and in MS Office programs. Adobe Acrobat also has lag when accessing menus and options in the tool bar, but other my other Adobe products have no issues. Assassins Creed Brotherhood also has lags, but its weird that it lags at start, but 5min into the game it plays rather smooth. There are sound issues though where the dialogue and background music sometimes disappears every couple of minutes but not enough to disrupt game play. Another person from a different site had the same problem in the game and found it was caused by a damaged hard drive.
Also, my old Toshiba laptop (which my lil sis now uses at home to play games) had a similar experience where I commute a lot with it and eventually the hard drive developed too many bumps and bad sectors it had to be replaced (according to the Toshiba technician).
Although I realize that I have been using CleanMyPC on my computer, and I think maybe I should stop it and reformat.