Of course you can take a ghost image of Win 2K machine.
I worked in a software testing lab and this is how we quickly switched machines from different versions of Windows running different versions of Office, AV, Browsers etc.
Ensure the PC you want an image of is set up with what you want on the image, and only what you want on the image.
Then, you should have a floppy disk which is the boot disk. Boot the machine with the floppy in place. You will then get a menu. Select the menu itme that allows you to write the image. Make sure the destination of the image has enough room to store it.
You will probably want to write the image to CD\DVD? If you have a network, write it to the a location on a machine somewhere (faster).
Basically that is it. I am not familiar with which ghosting software we were using at the time, but it was so simple. I am sure you can check Symantec's site for info on taking the image. But the steps above should cover it.
Cheers!