If you're running Pro, you can use GPEDIT.MSC to prevent Messenger from loading. Otherwise, even disabling it in startup won't cause it to "always" not run. Outlook, Outlook Express and some MS web pages can still make it load.
Start, Run and enter GPEDIT.MSC
For "per machine" restriction, go to Computer Configuration, Administrative Templates, Windows Components, Windows Messenger. For "per user" restriction, go to User Configuration, Administrative Templates, Windows Components, Windows Messenger.
You can now modify whether it starts initially and/or whether its to run at all.
Note: Outlook and Outlook Express will take longer to open, unless you turn off Messenger Support. In Outlook Express it is in Tools, Options, General tab. In Outlook it is in Tools, Options, Other.
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