Depends on the malware in question, how it spreads, and if you have networking/shared storage or any extra features enabled on your VM.
For example, if you have network sharing available on your VM from your host and the malware can spread via network shares...then yes it's possible it could spread to your host PC. Or if you have drives shared from the host PC to the VM, and the malware spreads via storage...then again yes it could spread to your host PC.