I went through the BIOS on my last computer, and you'd be surprised how much stuff was enabled that I would never use. You can definitely speed up the boot process and, I'm assuming, free up resources during normal operation.
It's a Gigabyte GA-X58A-UD9. So far, so good, it posted on the first try. The only problem is that the Silent Pipe (a really cool-looking heatsink gizmo for the North Bridge) doesn't fit if you're using the recommended extra power connections for 2+ graphics card setups... one of the cable receptacles is built RIGHT UNDER where it goes! Major, major design flaw that you'd think would have been noticed... who buys a motherboard this nice then only runs one card???