Ok strange, i got hit by a virus and i got it taken care of i think but now my computer just crashes if i dont mess with it for awhile, it goes to a bluescreen saying some error but when i push a keyboard button my desktop pops back up??
Check your display settings and see if the screen saver has been changed to one that displays a blue screen- I have seen those before. Right click on Desktop--> Properties.
Those are temp folders for applicaiton installers. They should be able to be deleted. If not find out how to take ownership of the files to get rid of them.
Phew looks like Windows hasn't been doing its job of deleting the temp folders there. I have the odd one that accidentally stays but that many will slow you down. Some of those updates are fairly large.