.....undoubtedly my problem is a hardware conflict (irq). But there are a number of issues that are inhibiting me from troubleshooting this issue properly. My ps/2 port doesn`t work (I would prefer to use that port over usb). My ps/2 port is not mentioned in cmos so I can`t activate it there. Also my mouse is reported twice, albeit in two different locations, within the device manager which doesn`t report it as an issue. When I try to uninstall either instance the mouse stops working completely. I have also tried uninstalling my usb hubs and letting them reinitiallize. Mouse doesn`t work until they are detected and reinitialized. My f8 function to boot in safe mode doesn`t seem to be working either. I am getting an error when my radeon tries to reconfigure through catalyst on start up (I think this very well may be related [don`t know why I keep going back to ati]).