Well yeah in a way. If you test drive software and then uninstall them, a lot of them don't do a through job of removing all remnants of the software.
Removing reg entries seems to be one thing most don't do.
Using a 3rd party uninstaller like WISE uninstaller will get rid of what is normally left behind. It has Forced and Safe uninstall modes. Safe mode does a normal uninstall. Forced has it take a real close look for anything that is a part of that software and presents it to let you decide if it needs to go.
I have used Forced to remove some software that doesn't have a good uninstaller routine. Like WAMP. It has an awful uninstaller. Leaves a lot of trash behind. WISE sweeps, mops, and squeegees the windows. Then spritzes air freshener.
Reg cleaners like CC become redundant. But still it's better to be safe than sorry. If you're not sure, don't bother with it.