I'm currently using x64 with no problems, all programs work fine, some are on wow, and some aren't, system's so fast you can't tell.
I'm also SLI with no problems.
Just make sure you get all the updates from M$, they've already ironed out most of the kinks.
The only concern I'd have is; isn't the core 2 duo architecture 32bit with two "channels", and not a true 64bit proc.?
Don't know if x64 will like that. Or am I mistaken?
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