I have a asus motherboard M3a79-t an OCZ ddr2 4gb 1066 heat pipe memory and a AMD x4 64 9950 processor. I also have a Radeon HD 4850 graphics. The only thing i have heard is that running the 64 bit vista that there isnt alot of drivers out there. I have not put this pc together yet. I also will be running two 500 sata hard drives with a 1000 watt Quattro power supply.