Well this is all based on user preference more than anything. I prefer to use NOD32 for Anti-Virus. Windows Defender Beta 2 for Anti-Spyware. Zone Alarm Pro for Firewall. Other than that it is things such as Opera 9 Beta. Firefox, IE7, Adobe Creative Suite, Gamegain, Alcohol 120%, Nero 7, AMP Font Viewer. It all depends on what you do with your PC.