I don't know about all popups but "Hitware Popup killer light" will block allmost all of them, I only have a popup every so often, and for some thing ezer to use try the google tool bar. It has a good one to.
Yeah Id agree, Opera is cool. But if you prefer using IE and your an XP user, download SP2, this has the most effective Pop Up killer I have ever seen.
You can configure the options in your IE tools menu when an IE window is open.
\" When those two tracks fit together to make the perfect harmony and the adrenaline of the crowd makes you fall to your knees, making your eyes water because your caught up in the moment.... thats when you know you are a real DJ \" - DJ Dayle
Firefox works well Ill give it that, but sometimes I cant recomend telling a user to switch browsers. Google toolbar works well for stopping pop-ups and a program called Spyware Guard is also great at blocking small hijack attempts. It will prompt you if your start page has changed and will ask if you want to keep the old entry or the new entry. Not bad stuff at all. theres my $0.02