Pardon the bluntness, but why not just use the damn START menu? That's what it's there for...To organize the stuff you access. (In other words, don't be a mess.)
I do tons of things on my main box, and I have a grand total of 8 icons on my desktop. Everything else (documents, programs, folders, etc) I keep neatly organized in my START menu for easy and quick access. That way, all my screens show nothing but the pretty pics I have set as wallpapers.