For trouble shooting drives and such. The SATA one would be useful,. but to use the other ones you would have to shut down your computer and pull it out anyway. It would only take a few seconds to take off your side panel and grab a molex connector. I guess it's kinda useful in theory, but in practicality, I dont know, I dont see a use. Like I said, the SATA one would be useful, but not the molex. Maybe if you were to run some internal parts on the outside of your computer, like a HDD that you cant fit inside for one reason or another. They should have made an IDE expansion as well.