keyboard , mouse not working

[DOTA2000]

When i play a computer sometimes my mouse and keyboard completely dont work at all and i keep hearding a beep noise, i try taking the plug out and put it back in but stil doesnt work. It works fine when im not playing computer games i just wanna know how i can fix this. Any help would do thanks
OS: windows xp

 

[sir nerdalot]

The beeping is most likely the system speaker. If thats correct then your computer is trying to tell you that something is wrong. What kind of mouse do you have? Also, what kind of keyboard? Like USB, PS/2 etc

 

[JinkX]

thats ture .. the beeping means that theres something wrong ..
probably its the keyboark thats making the noise ..
anyway .. whats the brands ??