Originally posted by mr_wizard
So it's more efficient when working with multiple programs?
Yes, it is immeasurably more efficient when working with multiple programs, but the multiple programs part isn't exclusive, as 64-bit processors are immeasurably more efficient at everything.
The only difference you might see is if you're some scientist doing high-end floating point calculations for some sort of extremely complicated gene sequencing or some crap like that. Daily user - there is no difference. I use 32-bit Linux because I use 32-bit software and it's a pain in the arse to run a 32-bit chroot or use the compatibility libraries, and since the advantage of 64-bit over 32-bit is so immeasurable, I just run native 32-bit Linux.