the p5w is a step up from the p5b-deluxe. They both should give you good oc's. The p5w come with 2 pci-e x16 slots for crossfire. The p5b only has 1 pci-e x16 and 1 pci-e x1,x4 (at max) (new egg says it has 2 pci-e x16 slots but one can only can go to x4).
If you dont want crossfire or sli, p5b-deluxe is awesome. If you want sli, you'll have to get the p5w(and dl hack drivers) or go with the striker turtile suggested(prob the best mobo out right now for the conroes, man i wish i had one of those and 2 8800gtx, that would be kick @$$ system