Higher end motherboard will enable you to acheive higher FSB, or HTT, depending if you CPU lets you go that far that is.
Also, as mentioned above, stability is something to be considered when buying a motherboard, even if you are not overclocking. You should also look at the different features, such as onboard sound if you are using, SPDIF, etc...
Asus is well known, and make solid stable motherboards. As is the MSI. Its really your choice, and what suits you the best.
My current specs:
Biostar TPower x58
XFI GTX260 Black Edition
640 WD Caviar Black
Vista Home Premium x64