Re: Cooler master....gtx280........support or not???
From the looks of the side with the panel off, it should fit in there. There's quite a bit of space between the motherboard tray and 3.5" drive bays. The GTX280 is around 10.5" or 26.7cm, so it will stick out an inch from the motherboard. I think it should fit fine as long as you don't install a hard drive in front of it.
Make sure you get a couple extra fans, because they only include a single 120mm fan. And that card is a bit of a heater. So get one for the front and side.