Honestly "003" the only problem that I see with that motherboard is the fact that the two PC slots are wedged between the two PCI express slots. This will make adding a x-fi card very tight with that monster of a videocard. But, if he's not going SLI it could be ok.
But if he does ever go SLI.... we'll it could be an issue.
I like ASUS. Everyone thinks they suck for AMD. I haven't had any experience with a ASUS AMD board so, i don't know. I'll tell you one thing though, the ASUS P4P800-E Deluxe is the best P4 s478 motherboard ever made though....