The latest cards are ATI's Radeon 5xxx series. The 5850 and 5870 are the best in, the latest by ATI. Nvidia's latest is the GTX295, which I believe is 2 GTX275's combined (Internal SLI connectors, giving a 1 card SLI setup)? The 5870's are 2 4890's, I believe, or comparable at least. The 5xxx series support DirectX 11, while no other cards do. A lot of the newer cards are dual slot designs, but the motherboard manufacturers understood this, and accommodated better placement of the PCI-E x16 slots far enough away from each other.