the dual channel seems to make a pretty big difference for myself (well actually im running triple channel now) ..also the default dual channel RAM slots are generally either 1&3 or 2&4....never next to each other like 1&2 or 3&4
haha with the new X58 chipsets in the socket 1366 boards they support tri-channel memory.... it's like dual channel ram...but with three...hhahahaha.....