Firstly, if you are going to do anything overclocking wise, why not get the 5400+ Black Edition, it runs hotter but overclocks better. Newegg.com - AMD Athlon 64 X2 5400+ Brisbane 2.8GHz 2 x 512KB L2 Cache Socket AM2 65W Dual-Core black edition Processor - Processors - Desktops
I guess you read this review AMD 780G & Athlon X2 4850e Review
Even so, is it for gaming and if so then you will need to change that card to something higher end for any respectable graphics. Decent cooler although again the ocz memory isn't the best, try some Ballistix (Tracers if you can stretch).
Those changes are if you can afford them, but in any case good, luck with your build