I had the same problem. Historically, I've gotten used to having to populate the memory slots starting with the slots closest to the CPU and working my way away.
Six slots, three sticks of tri-channel
I followed this rule and everything was stone-dead.
So I looked in the manual and it told me to start with the slots furthest from the CPU.
Everything worked after that.
I hope your problem is as simple. I would read the manual meticulously. It doesn't make sense that your mobo - and its replacement - were both bad. Even bad RAM or other components tend not to leave a computer stone-dead. I once saw a lightening-struck modem kill a computer, and another time a bad graphics card killed it, but each had become damaged from abusive external forces.
At work, I tired to get a high-end graphics card to function on a Dell PC with inadequate wattage, but your specs look like they ought to POST.
Is there any auxiliary power for the graphics card that maybe isn't connected?
You've probably already done this... unplug everything except for the CPU, memory, hard drive, graphics, keyboard, mouse.
No USB, firewire, eSATA connectors, no DVDs, no fancy stuff. Not even any case fans. Like patonb said, better to remove it from the case entirely. The point is more to see if it'll beep and/or POST, not necessarily to boot. By being on a piece of cardboard, you eliminate electrical shorts, too.