Lol, well sure if you're talking about the literal meaning of the word 'overdose'. If I eat too many cookies and go over my daily recommended sugar intake, then I'm 'overdosing' on sugar/cookies. Suddenly sounds a heck of a lot worse...
The implication/connotation when someone mentions an 'overdose' is a fatal overdose or at least coming close to death. As Overlord said, the amount you'd need for that is staggering/impossible.