If you have a DVD burner you should make frequent backups of your important data. Most viruses, excluding trojans, are usually located in your temp files, or backup files located in the windows directory. You should follow the path of the infected file to see where it is located. Most of the time you will be safe to delete the infected file and won't have any problems. For future protection from viruses, however, I would reccommend updating your virus software as often as possible to obtain the latest virus definitions and make sure it loads after each startup. McAfee is one of the better programs in my opinion, although others prefer Norton's line of AV products. In short, you should be ok deleting the files as long as the virus hasn't effected any major system files. Good luck.