I've heard rumors that the minimum will be a 6800GT, and thats for playing it 640x480 lowest settings. To play it 1024x768 Medium settings you will need at least 2 7800GTXs in SLI and a PhysX card. Anything higher than that you will need a GeForce 8 series card. The lowest Radeon card that will be able to play it is the X1800XL. Do you think this game will be that demanding?