Googled because it interested me... and nope, ISO's arent' compatible
https://forums.plex.tv/index.php/topic/39148-can-i-play-iso-files/
I never thought about ripping my library to .iso...
Meh, .mp4 and .avi work for me
Just installed it on my server and tested some music / channels on it. Need to hook up my external HDD's to it to test that out now lol.
Does it play MKV fine, or do you know? A lot of my media is also MKV.
Cheating casting it to my Chromecast through Chrome since I don't want to buy Premium lol. Worked pretty well for a few clips through the Channels section, as well as some songs through the actual streamer.