Well.....not necessarily. But you can attempt to figure it out, by taking the mobo out of the case and putting it on something anti-static (if you wind up REALLY frying something from not putting it on something good enough to not conduct electricity then well...I take no blame for it
) But anywho, place the motherboard on something that can't possibly conduct electricity. If you have your motherboard box that would do, just put the anti static bag over the box then set on the mobo. Plug in JUST the keyboard, RAM, and video card and see if you atleast get a beep and could possibly get into the BIOS. If it does then you could be grounding the mobo in the case or a HD is bad, or possibly you just had a loose connection somewhere.