Are the spacers installed to isolate the mobo from the bottom of the case? Verify that first...... otherwise your mobo will be history when you power-up.
Are the power & Hdd leds " ON" when you power-up?? If not then:
Verify the power-on, reset sw., led connectors are connected to the mobo connector properly.
If all the above is correct, just try to "Post" with video card, and 1 stick of Ram, disconnect Hdd and Cd/Rom drives.
* Trying to Post with 'audio beep codes'.
Take your time..... don't hurry!
** Enter your System components in your profile...... so we know what you have. Include exact power supply model!