if you are wantig to replace your main heat sink, NO, unless you want that to be perment, I use that for like ramsinks and other weird heatsinks, but not for cpu, vga, chipset, or any other fans, this is because, if you have to raplace the part well you just lost a nice heat sink, because that stuff is VERY HARD to get off. Also heatsinks that have fans, sometimes wear out and so you will have to replace them, and that will be harder then anything to get the heatsink off, and you might even damage the chip while doing it.