since you have PCI-E I'd suggested a DFI Ultra-D board, basically the best OC'ing board out there, but yeaaaaah it's also kind of advanced especially in the RAM section but there's plenty hear to help you out with that.
As long as you keep your CPU cool, practice safe OC'ing techniques, use common sense, go in small steps, and keep on top of keeping it stable you'll be aright.
It's the people who push it huge steps at a time, run prime95 for 2 minutes, call it stable and push it more that wind up screwing something up.
It is best to OC your RAM along with your CPU, because just raising the CPU HTT beyond 200 will simply be bottlenecking your RAM and CPU, but will still OC your CPU.......
Most people will OC the CPU to say 300HTT but use a divider to keep their RAM at like 250MHz, still technically a bottleneck, but with those speeds it doesn't really matter