Well, depending on what interface you want, IDE can support up to four devices, and motherboards now come standard with four SATA connections. That's 8 devices right there.
Check out some of the new DFI AMD motherboards on newegg, such as one using the nForce4 Chipset.
Using that board you can have each drive have its own SATA connection. CD drives don't have SATA interfaces so you can use pretty much just one IDE cable for them.
In the case of the hard drives being IDE interface, there are boards that have two IDE cable connections, most motherboards come with 2 now anyways, so totaling 4 possible IDE connections