3D-Labs makes some awsome high-end cards. We got a couple of $1400 dual-chip cards here at the office for CAD work and modeling.
If you do serious graphics work, there are companies (like 3D-Labs and ATI) who will build you a powerful card. In reality, the cards coming out to our desktops today (such as the x800 and 6800) are "mainstream" cards. No one at Pixar, ILM, MGM, etc, is using a x800 for work! Those people would rather blow up a maseratii than their boxes.